AeroLab Reading room

Biology / IGCSE

Biotechnology and genetic modification

Biotechnology uses organisms or biological processes to make useful products.

Learning objectives

The big idea

Biotechnology uses organisms or biological processes to make useful products. Yeast fermentation can produce ethanol and carbon dioxide; controlled fermenters regulate factors such as temperature, nutrients and contamination.

Genetic modification changes genetic material, for example by introducing a gene enabling a production cell to make a useful protein. The outcome depends on expression and biological context. Product safety, ecosystem effects and access need case-specific evidence, not assumptions that all modifications have identical risks.

Worked example

A supplied fermenter dataset shows 12 g product from 3 dm³ culture. Find product per dm³.

Follow the solution

Divide mass by culture volume: 12/3=4 g per dm³.

Investigate and explain

Using the worked example as supplied data, predict the effect of changing one condition. Draw a labelled model, record your reasoning and identify a variable that would need controlling. No human, animal or microbial experiment is required.

Related simplified PhET model. Explain what it represents and what the living system does differently.

Open the interactive investigation

Check your understanding

1. Which organism commonly produces carbon dioxide in bread making?

  1. A red blood cell
  2. A virus
  3. Yeast
Check the answer and reasoning

Yeast

Yeast metabolises sugars and releases carbon dioxide that expands the dough.

2. A supplied fermenter dataset shows 12 g product from 3 dm³ culture. Find product per dm³.

  1. 4 g/dm³
  2. 36 g/dm³
  3. 0.25 g/dm³
Check the answer and reasoning

4 g/dm³

Divide mass by culture volume: 12/3=4 g per dm³.

3. Is every use of microorganisms genetic modification?

  1. Yes
  2. No
  3. Only in food production
Check the answer and reasoning

No

Traditional fermentation can use unmodified organisms; genetic modification specifically changes genetic material.