AeroLab Reading room

Biology / AS level

Practical skills: measurements and evidence

Good practical work links a question to a measurable variable, a suitable comparison and controlled conditions.

Learning objectives

The big idea

Good practical work links a question to a measurable variable, a suitable comparison and controlled conditions. Biological replication samples organism-to-organism variation; repeated readings of one specimen address a different source of variability.

Use clear tables, appropriate units and justified precision. Draw observations with labelled structures rather than invented detail. Consider hazards, consent and organism welfare when selecting methods; supplied images and datasets can practise analysis without collecting new biological material.

Worked example

A count is 10, 12 and 14 in three independent samples. Find the mean.

Follow the solution

Add 10+12+14=36 and divide by three independent samples to obtain 12.

Investigate and explain

Using the worked example as supplied data, predict the effect of changing one condition. Draw a labelled model, record your reasoning and identify a variable that would need controlling. No human, animal or microbial experiment is required.

No exact PhET model is claimed for this topic. Use diagrams and supplied-data reasoning instead.

Open the interactive investigation

Check your understanding

1. Why use independent biological replicates?

  1. To sample biological variability
  2. To make every result identical
  3. To remove all systematic error
Check the answer and reasoning

To sample biological variability

Different specimens can vary even under similar conditions, so independent replication informs that variation.

2. A count is 10, 12 and 14 in three independent samples. Find the mean.

  1. 36
  2. 12
  3. 14
Check the answer and reasoning

12

Add 10+12+14=36 and divide by three independent samples to obtain 12.

3. Can extra decimal places compensate for a poorly resolved measurement?

  1. Yes
  2. Only with a calculator
  3. No
Check the answer and reasoning

No

Reported precision must reflect the measurement method; additional digits do not add information.