Biology / AS level
Cell membranes and transport
A phospholipid bilayer forms a hydrophobic barrier containing proteins with transport, receptor and catalytic roles.
Learning objectives
- Explain the fluid-mosaic model.
- Compare membrane transport pathways.
- Predict net water movement from water potential.
The big idea
A phospholipid bilayer forms a hydrophobic barrier containing proteins with transport, receptor and catalytic roles. Membrane components move laterally, while cholesterol helps regulate membrane properties in animal cells.
Simple diffusion and facilitated diffusion move substances down relevant gradients without direct ATP use. Active transport uses energy to move against gradients. Water moves from higher to lower water potential across a partially permeable membrane; pressure as well as solutes can affect that potential.
Worked example
Two compartments have water potentials −100 kPa and −300 kPa. Which way is net water movement if only water can cross?
Follow the solution
−100 kPa is the higher water potential, so water moves toward −300 kPa until the relevant potentials balance.
Investigate and explain
Using the worked example as supplied data, predict the effect of changing one condition. Draw a labelled model, record your reasoning and identify a variable that would need controlling. No human, animal or microbial experiment is required.
Related simplified PhET model. Explain what it represents and what the living system does differently.
Open the interactive investigation
Check your understanding
1. Which part of a phospholipid faces the aqueous surroundings?
- Hydrophobic tails only
- Hydrophilic head
- Every part equally
Check the answer and reasoning
Hydrophilic head
Polar heads interact with water while nonpolar tails gather within the bilayer.
2. Two compartments have water potentials −100 kPa and −300 kPa. Which way is net water movement if only water can cross?
- From −300 to −100 kPa
- No movement because both are negative
- From −100 to −300 kPa
Check the answer and reasoning
From −100 to −300 kPa
−100 kPa is the higher water potential, so water moves toward −300 kPa until the relevant potentials balance.
3. Does facilitated diffusion necessarily require ATP directly?
- No
- Yes
- Only for glucose
Check the answer and reasoning
No
A channel or carrier can support passive movement down a gradient without direct ATP hydrolysis.