AeroLab Reading room

Biology / AS level

Infectious diseases and transmission

Infectious diseases involve pathogens with different biological properties.

Learning objectives

The big idea

Infectious diseases involve pathogens with different biological properties. Cholera bacteria can spread through contaminated water, tuberculosis through airborne transmission and malaria through a mosquito vector; control must address the relevant route.

Antibiotics act on susceptible bacterial processes. Resistance can arise through mutation or acquired genes, then spread when selection favours resistant variants. Public-health outcomes also depend on infrastructure, access and coordinated prevention rather than the pathogen alone.

Worked example

A supplied sample has 15 resistant colonies among 60 tested. Find the resistant proportion.

Follow the solution

15/60=0.25, or 25%; the estimate describes this sample and testing method.

Investigate and explain

Using the worked example as supplied data, predict the effect of changing one condition. Draw a labelled model, record your reasoning and identify a variable that would need controlling. No human, animal or microbial experiment is required.

No exact PhET model is claimed for this topic. Use diagrams and supplied-data reasoning instead.

Open the interactive investigation

Check your understanding

1. Which is a vector for malaria transmission?

  1. A red blood cell as an airborne carrier
  2. A mosquito
  3. A bacterium in drinking water
Check the answer and reasoning

A mosquito

An infected female Anopheles mosquito can transmit the malaria parasite.

2. A supplied sample has 15 resistant colonies among 60 tested. Find the resistant proportion.

  1. 75%
  2. 4%
  3. 25%
Check the answer and reasoning

25%

15/60=0.25, or 25%; the estimate describes this sample and testing method.

3. Does antibiotic exposure intentionally direct a bacterium’s mutation toward usefulness?

  1. No
  2. Yes
  3. Only if exposure is prolonged
Check the answer and reasoning

No

Mutation is not purposeful; exposure changes which variants survive and reproduce.