AeroLab Reading room

Biology / AS level

Biological molecules and water

Monosaccharides form polysaccharides, amino acids form polypeptides and nucleotides form nucleic acids.

Learning objectives

The big idea

Monosaccharides form polysaccharides, amino acids form polypeptides and nucleotides form nucleic acids. Condensation forms a bond with water produced; hydrolysis uses water to break a bond. Triglycerides contain glycerol and three fatty acids rather than being repeating-unit polymers.

Hydrogen bonding contributes to water’s cohesion and thermal properties. Protein function depends on folding and interactions among side chains; a change in sequence or conditions can alter shape. Cellulose and starch both contain glucose units but differ in linkage and organisation.

Worked example

How many peptide bonds join five amino acids into one unbranched chain?

Follow the solution

Connecting five units in a single chain requires four links, each formed between adjacent amino acids.

Investigate and explain

Using the worked example as supplied data, predict the effect of changing one condition. Draw a labelled model, record your reasoning and identify a variable that would need controlling. No human, animal or microbial experiment is required.

No exact PhET model is claimed for this topic. Use diagrams and supplied-data reasoning instead.

Open the interactive investigation

Check your understanding

1. Which reaction breaks a glycosidic bond using water?

  1. Condensation
  2. Transcription
  3. Hydrolysis
Check the answer and reasoning

Hydrolysis

Hydrolysis consumes water during bond cleavage.

2. How many peptide bonds join five amino acids into one unbranched chain?

  1. 4
  2. 5
  3. 10
Check the answer and reasoning

4

Connecting five units in a single chain requires four links, each formed between adjacent amino acids.

3. Are starch and cellulose interchangeable simply because both contain glucose?

  1. Yes
  2. No
  3. Only in plants
Check the answer and reasoning

No

Different glycosidic linkages and chain arrangements produce different structures and properties.