AeroLab Reading room

Biology / A2 level

Control and coordination

Membrane ion gradients and selective channels support resting potentials and action potentials.

Learning objectives

The big idea

Membrane ion gradients and selective channels support resting potentials and action potentials. An action potential propagates through local electrical changes; myelination alters how efficiently distant regions of axon are activated.

Chemical synapses release neurotransmitter that binds postsynaptic receptors. Summation influences whether a new action potential occurs. Hormonal and plant signalling use different mechanisms, including growth responses associated with auxin distribution; a response is a regulated process rather than a conscious choice by the tissue.

Worked example

An impulse travels 0.6 m in 0.02 s. Find mean propagation speed.

Follow the solution

Divide distance by time: 0.6/0.02=30 m/s.

Investigate and explain

Using the worked example as supplied data, predict the effect of changing one condition. Draw a labelled model, record your reasoning and identify a variable that would need controlling. No human, animal or microbial experiment is required.

Related simplified PhET model. Explain what it represents and what the living system does differently.

Open the interactive investigation

Check your understanding

1. What crosses a typical chemical synaptic cleft?

  1. The entire presynaptic neuron
  2. Neurotransmitter molecules
  3. A continuous stream of action potentials as particles
Check the answer and reasoning

Neurotransmitter molecules

Electrical activity triggers chemical release; the transmitter diffuses and binds receptors.

2. An impulse travels 0.6 m in 0.02 s. Find mean propagation speed.

  1. 0.012 m/s
  2. 3 m/s
  3. 30 m/s
Check the answer and reasoning

30 m/s

Divide distance by time: 0.6/0.02=30 m/s.

3. Does a stronger stimulus normally make each action potential taller?

  1. No
  2. Yes
  3. Only in a myelinated axon
Check the answer and reasoning

No

Action potentials are approximately all-or-nothing; stimulus intensity is often encoded through firing frequency and recruitment.